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From the Wall Street Journal:

In the amaranthine adventure for a phenomenon diet pill, Americans are aggravating an arrangement of decree drugs accustomed by the Food and Biologic Administration to amusement a array of illnesses. None of them accept been accustomed as diet drugs — but for many, weight accident is a ancillary effect.

The account includes drugs meant to amusement attention-deficit hyperactivity ataxia (Adderall and Ritalin), abasement (Wellbutrin), attack (Topamax and Zonegran), diabetes (Glucophage and Byetta), beddy-bye disorders (Provigil), smoker (Zyban) and alike analgesic overdoses (Narcan). Often these drugs are acclimated alone, but sometimes they’re taken in aggregate with anniversary added or with accepted weight-loss medications, such as phentermine.

The doctors who appoint drugs off-label for weight accident accept they ample a void. “Obesity is a abiding ache — diet and exercise aren’t abundant for abiding weight accident for best patients,” says Robert Skversky, a bariatric physician in Newport Beach, Calif. “Chronic diseases charge drugs to accumulate them beneath control.”

Dr. Skversky uses a aggregate of drugs he adjusts for anniversary accommodating — a biologic cocktail usually consisting of phentermine additional antidepressants such as Prozac, antiseizure drugs such as Topamax or Zonegran, or diabetes drugs such as Glucophage or Byetta. (Ms. Krawczyk, who is one of his patients, takes Adipex, or phentermine; the antidepressants Wellbutrin and Celexa; and Topamax.) A aggregate of these drugs could amount about $100 to $200 a ages or more, says Dr. Skversky.

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